20+20 Vision tells the story of Athinoula A. Martinos Center for Biomedical Imaging across its forty years of existence, from its origins in the early 1980s to the many ways it rose to meet the unprecedented challenges of the COVID-19 pandemic. The book spotlights the science, the technology and, most importantly, the people behind the Center's innumerable successes and collects more than 150 images illustrating its long, eventful history.