Uprooted from her old life, Eliza Peel and her family adjust to a new city and a new community after inheriting a colossal mansion from an estranged relative. But the reclusive family member who gave this mansion to Eliza's family was harboring a startling secret. Flitting about the mansion are hundreds of lost souls which seem to have plans for Eliza. Though Eliza begins to form friendships with some of the haunted house's ghosts, life soon gets more complicated with the arrival of a bungling ghost-hunter and a supernatural predator that has stalked the world for centuries. Throughout these dilemmas, Eliza attempts to discover her place in life: in her school, her family, and in the new home she shares with the dead.