Keeping Laughter Alive is doctor recommended and should be taken any time you need a laugh or deep thought. It is best taken with your morning coffee, at work on a rough day, or even before you go to bed. Side effects include inspiration, encouragement, smiling and in 50% of patients over-active laughing. You should not take this while driving as it may cause you to giggle at drivers next to you. It is appropriate to wear certain protective gear while taking this medication such as funny shirts, wacky hats, or even a red nose; as it will cause others to giggle thereby making there day better. Please remember to always take with a tall glass of spring water slinky included. Above all else just remember keep smiling!