This doctoral research explores doctoral supervision within life science research in a Danish university. From one angle it investigates doctoral studentsÕ experiences with strengthening the relationship with their supervisors through a structured meeting with the supervisor, prepared as part of an introduction course for new doctoral students. This study showed how the course provides an effective way to build supervisee agency and strengthening supervisory relationships through clarification and alignment of expectations and sharing goals about doctoral studies. From the other angle the research investigates learning opportunities in supervision with multiple supervisors.