100 years from now.
Society is addressing the effects of global warming and extreme weather as well as fighting a terrifying and inexplicable epidemic - at age 40, about 50% of the world population spontaneously turns into the opposite sex.
Humanity is reassessing culture, customs and personal relationships in light of this life-altering change.
Marina and Josh have been married for 18 years - they live in Los Angeles, they love each other. Josh is now 42 and went through his 40th birthday unscathed. Marina is turning 40 in 5 days.